Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 185
interventional 101
Observational 80
Registry 4

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Device 31
Drug 19
Biological 9
Procedure 9
Other 6
Drug|placebo 5
Biological|placebo 4
Behavioral 3
Device|Other 2
Device|Procedure 2
Behavioral|Device 1
Behavioral|Drug|Procedure 1
Biological|Drug 1
Device|Diagnostic Test 1
Device|Other|Procedure 1
Diagnostic Test 1
Diagnostic Test|Drug|Other 1
Dietary Supplement 1
Drug|Other 1
Drug|Procedure 1
Other|Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 51
France 13
NA 6
Canada 4
Switzerland 3
Austria|Germany 2
Korea, Republic of 2
United Kingdom 2
United States|Austria|Canada|Czechia|France|Germany|Poland|Spain|United Kingdom 2
United States|Russian Federation 2
Australia 1
Australia|Austria|Belgium|Czechia|France|Germany|Hungary|Poland|Portugal|Russian Federation|Ukraine 1
Croatia 1
Germany 1
Hong Kong 1
Hungary 1
Israel 1
Japan 1
Philippines 1
Taiwan 1
Thailand 1
United States|Austria|France|Germany|Spain|United Kingdom 1
United States|Canada 1
United States|Canada|Czech Republic|Germany|Hungary|India|Philippines|Poland|Russian Federation|Serbia|Singapore|Slovakia|South Africa|Taiwan|Thailand|United Kingdom 1

Sites per Study

Site_count Study_Count
1 74
2 8
4 1
5 3
7 2
10 1
11 1
16 1
18 1
21 1
22 1
41 1
42 1
43 1
57 1
65 1
75 1
106 1

Phase

Phase Study_Count
N/A 42
Phase 3 16
Phase 2 14
Phase 4 13
Phase 1 7
Phase 1/Phase 2 7
Early Phase 1 1
Phase 2/Phase 3 1

Number of Arms

Number_of_Arms Count_of_Studies
1 26
2 49
3 5
4 5
5 1
6 1
NA 14

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 80 5.0000 2.00000 9.00000 8.00 15 19.000 10.00000
1st Qu. 80 14.2500 7.50000 14.00000 15.25 15 59.750 17.00000
Median 80 32.0000 11.00000 18.00000 23.00 15 114.000 30.00000
Mean 80 46.7381 22.14286 17.71429 48.50 15 167.125 98.15385
3rd Qu. 80 50.0000 28.50000 22.00000 39.75 15 250.000 100.00000
Max. 80 200.0000 70.00000 25.00000 242.00 15 516.000 502.00000

Trial Group Type

group_type Group_Count
Experimental 70
Active Comparator 51
Placebo Comparator 19
Other 16
NA 14
No Intervention 8
Sham Comparator 6

Intervention Model

intervention_model Study_Count
Parallel Assignment 43
Single Group Assignment 30
Crossover Assignment 21
NA 5
Factorial Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 75
Basic Science 11
Diagnostic 5
Other 5
Supportive Care 3
Health Services Research 1
NA 1

Observational Studies

Studies by Country

Country Study_Count
United States 55
France 6
Japan 2
Australia|Belgium|Czechia|France|Germany|Netherlands|Portugal|Russian Federation|United Kingdom 1
Austria 1
Austria|Germany 1
Canada 1
China 1
Croatia|France|Germany|Slovenia 1
France|Germany|Russian Federation 1
Mexico|United Kingdom 1
NA 1
Norway 1
Norway|United Kingdom 1
United Kingdom 1
United States|Algeria|Australia|Austria|Belgium|Brazil|China|Czechia|Estonia|France|Germany|Hungary|Israel|Italy|Jordan|Korea, Republic of|Latvia|Lebanon|Malaysia|Mexico|Philippines|Poland|Portugal|Romania|Russian Federation|Serbia|Singapore|Slovenia|Sweden|Taiwan|Thailand|Turkey|United Arab Emirates|United Kingdom 1
United States|Australia|Canada|France|Germany|Italy|United Kingdom 1
United States|Canada|Germany|Italy 1
United States|Germany 1
United States|Germany|Taiwan 1

Sites per Study

Site_count Study_Count
1 64
2 5
5 2
8 1
9 1
11 1
36 1
39 1
42 1
45 1
70 1
113 1

Enrollment Metrics

Measure Observational
Min 2.00
1st Qu 35.25
Median 68.50
Mean 360.65
3rd Qu 210.00
Max 5000.00

Observation Model

observational_model Study_Count
NA 26
Cohort 21
Case-Control 11
Case-Only 9
Other 7
Case Control 4
Ecologic or Community 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 46
NA 16
Cross-Sectional 11
Retrospective 5
Other 2

Registries

Studies by Country

Country Study_Count
United States 3
Korea, Republic of 1

Sites per Study

Site_count Study_Count
1 4

Enrollment Metrics

Measure Registries
Min 40
1st Qu 85
Median 100
Mean 110
3rd Qu 125
Max 200

Registry Model

observational_model Study_Count
Cohort 3
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 2
Cross-Sectional 1
Other 1

Follow-up

target_duration Study_Count
1 Day 1
10 Years 1
20 Years 1
3 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03889704 Neuromuscular Electrical Stimulation for Jaw-closing Dystonia https://ClinicalTrials.gov/show/NCT03889704 Recruiting University of Pittsburgh 2020-07-01
NCT03409120 Unlocking Dystonia From Parkinson’s Disease With Directional DBS Technology https://ClinicalTrials.gov/show/NCT03409120 Enrolling by invitation University of Alabama at Birmingham 2020-12-31
NCT03381456 Task-dependent Operation of a Mechanism Intracortical Inhibition in Dystonia https://ClinicalTrials.gov/show/NCT03381456 Completed University Hospital, Lille 2017-04-30
NCT03369613 Transcranial Electrical Stimulation for Cervical Dystonia https://ClinicalTrials.gov/show/NCT03369613 Recruiting University of Colorado, Denver 2020-12-31
NCT03318120 Exercise Training in Dystonia https://ClinicalTrials.gov/show/NCT03318120 Recruiting University of Florida 2020-12-01
NCT03270189 Effect of the Visual Information Change in Functional Dystonia https://ClinicalTrials.gov/show/NCT03270189 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2021-10-31
NCT03232320 Meditoxin® Treatment in Patients With Cervical Dystonia https://ClinicalTrials.gov/show/NCT03232320 Completed Medy-Tox 2018-10-31
NCT03078816 Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults https://ClinicalTrials.gov/show/NCT03078816 Completed University of California, San Francisco 2019-07-24
NCT03074422 Effectiveness and Reliability of Hypnosis in Stereotaxy https://ClinicalTrials.gov/show/NCT03074422 Recruiting University Hospital, Geneva 2019-07-30
NCT03019458 MINGO Supplemental Trial in X-linked Dystonia-Parkinsonism Patients https://ClinicalTrials.gov/show/NCT03019458 Completed Sunshine Care Foundation 2017-05-08
NCT02957942 rTMS in Spasmodic Dysphonia https://ClinicalTrials.gov/show/NCT02957942 Completed University of Minnesota 2018-12-31
NCT02882334 Finger Individuation Training With a Training Device Versus Conventional Rehabilitation for Writer’s Cramp https://ClinicalTrials.gov/show/NCT02882334 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2021-12-31
NCT02834871 Integration of the Cervical Proprioceptive Signals in Patients With Cervical Dystonia https://ClinicalTrials.gov/show/NCT02834871 Completed Fondation Ophtalmologique Adolphe de Rothschild 2015-07-31
NCT02727361 Role of the Striatal Cholinergic System in the Pathophysiology of Dystonia https://ClinicalTrials.gov/show/NCT02727361 Completed University Hospital, Bordeaux 2018-03-01
NCT02662530 Clinical and Kinematic Assessment for Determination of Botox® Injection Parameters in Cervical Dystonia https://ClinicalTrials.gov/show/NCT02662530 Active, not recruiting Western University, Canada 2020-12-31
NCT02618889 OnabotulinumtoxinA in the Management of Psychogenic Dystonia https://ClinicalTrials.gov/show/NCT02618889 Completed University of Cincinnati 2017-05-30
NCT03608397 Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1) https://ClinicalTrials.gov/show/NCT03608397 Completed Revance Therapeutics, Inc. 2019-12-03
NCT01581580 Deep Brain Stimulation Surgery for Movement Disorders https://ClinicalTrials.gov/show/NCT01581580 Recruiting National Institutes of Health Clinical Center (CC) 2021-10-01
NCT02504905 Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing https://ClinicalTrials.gov/show/NCT02504905 Recruiting National Institutes of Health Clinical Center (CC) 2021-06-30
NCT02552628 WILSTIM - DBS (WILson STIMulation - Deep Brain Stimulation) https://ClinicalTrials.gov/show/NCT02552628 Recruiting Hospices Civils de Lyon 2022-01-31
NCT02542839 rTMS and Botulinum Toxin in Primary Cervical Dystonia https://ClinicalTrials.gov/show/NCT02542839 Recruiting University of Florida 2020-09-30
NCT02420106 Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia https://ClinicalTrials.gov/show/NCT02420106 Completed New York Institute of Technology 2019-02-28
NCT02334683 Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia https://ClinicalTrials.gov/show/NCT02334683 Recruiting Icahn School of Medicine at Mount Sinai 2020-08-31
NCT02326818 Comparison of Electrophysiologic and Ultrasound Guidance for Onabotulinum Toxin A Injections in Focal Upper Extremity Dystonia and Spasticity https://ClinicalTrials.gov/show/NCT02326818 Completed National Institutes of Health Clinical Center (CC) 2020-03-26
NCT02252380 ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders https://ClinicalTrials.gov/show/NCT02252380 Active, not recruiting InSightec 2021-12-31
NCT02199509 Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia https://ClinicalTrials.gov/show/NCT02199509 Completed National Institutes of Health Clinical Center (CC) 2016-03-31
NCT02177617 Neurotoxin and Physical Therapy https://ClinicalTrials.gov/show/NCT02177617 Completed University of Florida 2017-01-07
NCT02131467 Safety and Tolerability of Perampanel in Cervical Dystonia https://ClinicalTrials.gov/show/NCT02131467 Completed University Health Network, Toronto 2020-02-28
NCT02107261 Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician’s Hand https://ClinicalTrials.gov/show/NCT02107261 Recruiting Icahn School of Medicine at Mount Sinai 2020-07-31
NCT02073630 Contribution of the Cerebellum In Sensory-motor Adaptation Via Gamma Oscillations: the Case of Dystonia https://ClinicalTrials.gov/show/NCT02073630 Completed Institut National de la Santé Et de la Recherche Médicale, France 2016-02-29
NCT02015039 Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer’s Cramp https://ClinicalTrials.gov/show/NCT02015039 Completed National Institutes of Health Clinical Center (CC) 2016-09-13
NCT01934296 Chronic Effects of DBS in Parkinson’s Disease and Dystonia https://ClinicalTrials.gov/show/NCT01934296 Active, not recruiting University of California, San Francisco 2020-12-31
NCT01921270 Dysport for the Treatment of OMD https://ClinicalTrials.gov/show/NCT01921270 Completed Emory University 2017-02-08
NCT01884064 Repetitive Transcranial Magnetic Stimulation for the Treatment of Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT01884064 Completed University of Minnesota 2010-07-31
NCT01860196 Efficacy and Safety of Meditoxin® Injection for Cervical Dystonia in Adults With Cerebral Palsy https://ClinicalTrials.gov/show/NCT01860196 Completed Seoul National University Hospital 2017-03-31
NCT01859247 Identification of Optimal Stimulation Site for Cervical Dystonia Symptoms: An Exploratory Study https://ClinicalTrials.gov/show/NCT01859247 Completed University of New Mexico 2014-06-30
NCT01806805 Efficacy Trial of Zonisamide for Myoclonus Dystonia https://ClinicalTrials.gov/show/NCT01806805 Completed Assistance Publique - Hôpitaux de Paris 2014-07-31
NCT01753336 Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia https://ClinicalTrials.gov/show/NCT01753336 Completed Ipsen 2015-10-31
NCT01753310 Efficacy and Safety of DYSPORT® Using 2mL Dilution in Adults With Cervical Dystonia. https://ClinicalTrials.gov/show/NCT01753310 Completed Ipsen 2014-10-31
NCT01738581 rTMS and Retraining in Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT01738581 Completed University of Minnesota 2015-06-30
NCT01698450 Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders https://ClinicalTrials.gov/show/NCT01698450 Completed University Children’s Hospital, Zurich 2013-12-31
NCT01681888 Surface EMG Biofeedback for Children With Cerebral Palsy https://ClinicalTrials.gov/show/NCT01681888 Recruiting University of Southern California 2020-01-31
NCT01588574 Study for Determine the Safety and Efficacy of Clostridium Botulinum Toxin Type A in Subjects With Cervical Dystonia https://ClinicalTrials.gov/show/NCT01588574 Completed Medy-Tox 2013-10-31
NCT01497639 Comparison of the Efficacy of Double Monopolar Versus Interleaving Stimulation Modes for Pallidal Deep Brain Stimulation https://ClinicalTrials.gov/show/NCT01497639 Completed University of Pecs 2018-06-07
NCT01495897 Abnormal Movements, Cerebellum and Sensorimotor : Oculomotor Study https://ClinicalTrials.gov/show/NCT01495897 Completed Institut National de la Santé Et de la Recherche Médicale, France 2014-03-31
NCT01486264 Open-Label Non-Inferiority Study Evaluating the Efficacy and Safety of Xeomin® in Subjects With Cervical Dystonia Flex https://ClinicalTrials.gov/show/NCT01486264 Completed Merz North America, Inc. 2016-03-29
NCT01433757 Ampicillin for DYT-1 Dystonia Motor Symptoms https://ClinicalTrials.gov/show/NCT01433757 Completed University of Florida 2017-06-30
NCT01384214 Effect of Botulinum Toxin Type A on Swallowing in Patients With Cervical Dystonia https://ClinicalTrials.gov/show/NCT01384214 Completed Allergan 2009-06-30
NCT03223623 Pathophysiology of Dystonia and Complex Regional Pain Syndrome https://ClinicalTrials.gov/show/NCT03223623 Recruiting National Institutes of Health Clinical Center (CC) 2021-12-31
NCT03307161 Osteopathic Manual Treatment Parkinson’s Disease and Truncal Dystonia https://ClinicalTrials.gov/show/NCT03307161 Recruiting New York Institute of Technology 2019-10-31
NCT03977493 IncobotulinumtoxinA (Xeomin) to Treat Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT03977493 Recruiting Ente Ospedaliero Cantonale, Bellinzona 2020-12-31
NCT03946046 Targeting Methods of Botulinum Toxin Injections for Cervical Dystonia https://ClinicalTrials.gov/show/NCT03946046 Recruiting University Hospital, Lille 2020-03-27
NCT03905304 Efficacy and Safety of MEDITOXIN® in Cervical Dystonia https://ClinicalTrials.gov/show/NCT03905304 Completed Medy-Tox 2014-07-30
NCT03805152 Abobotulinum Toxin and Neubotulinum Toxin Injection in Cerivical Dystonia https://ClinicalTrials.gov/show/NCT03805152 Enrolling by invitation Rajavithi Hospital 2020-11-30
NCT03797638 Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer’s Cramp and in Control Subjects https://ClinicalTrials.gov/show/NCT03797638 Completed Fondation Ophtalmologique Adolphe de Rothschild 2019-07-19
NCT03779308 Whole Body Vibration for Dystonia Cerebral Palsy https://ClinicalTrials.gov/show/NCT03779308 Completed The Hong Kong Polytechnic University 2019-10-30
NCT03753945 Spine MRI in Patients With Deep Brain Stimulation (DBS) https://ClinicalTrials.gov/show/NCT03753945 Recruiting University Health Network, Toronto 2021-01-01
NCT03664375 Impact Of Physiotherapy And Botox In Improving Functional Outcomes Among Post Stroke Focal Dystonia Patients https://ClinicalTrials.gov/show/NCT03664375 Completed Isra University 2016-08-31
NCT03617367 Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-OLS) https://ClinicalTrials.gov/show/NCT03617367 Recruiting Revance Therapeutics, Inc. 2021-11-30
NCT03587350 Assessing Cervical Dystonia https://ClinicalTrials.gov/show/NCT03587350 Completed The Leeds Teaching Hospitals NHS Trust 2018-01-31
NCT03582891 The Motor Network in Parkinson’s Disease and Dystonia: Mechanisms of Therapy https://ClinicalTrials.gov/show/NCT03582891 Recruiting University of California, San Francisco 2025-07-01
NCT01261611 Study Comparing Short Term Efficacy of Dysport and Dysport NG to Placebo, and to Assess Efficacy and Safety of Dysport NG of Subjects With Cervical Dystonia https://ClinicalTrials.gov/show/NCT01261611 Completed Ipsen 2012-05-31
NCT00998660 RECHARGE Sub-Study to the Implantable Systems Performance Registry (ISPR) https://ClinicalTrials.gov/show/NCT00998660 Completed MedtronicNeuro 2013-07-31
NCT00950664 A Study to Compare Dysport® and Botox® in the Treatment of Cervical Dystonia https://ClinicalTrials.gov/show/NCT00950664 Completed Seoul National University Hospital 2011-01-31
NCT00950196 Amantadine for Improving Neurologic Symptoms in Ataxia-Telangiectasia https://ClinicalTrials.gov/show/NCT00950196 Completed Sheba Medical Center 2009-11-30
NCT00942851 A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm https://ClinicalTrials.gov/show/NCT00942851 Completed National Institutes of Health Clinical Center (CC) 2010-10-31
NCT00878787 Theta-burst Transcranial Magnetic Stimulation https://ClinicalTrials.gov/show/NCT00878787 Completed University of Southern California 2010-01-31
NCT04299087 Repetitive Transcranial Magnetic Stimulation (rTMS) for Dystonia and Tremor https://ClinicalTrials.gov/show/NCT04299087 Recruiting University of Florida 2026-02-28
NCT03938363 Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal Dystonia https://ClinicalTrials.gov/show/NCT03938363 Recruiting University Hospital, Grenoble 2021-06-02
NCT01823237 Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia https://ClinicalTrials.gov/show/NCT01823237 Recruiting Emory University 2019-12-31
NCT02911103 Deep Brain Stimulation Surgery for Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT02911103 Recruiting National Institutes of Health Clinical Center (CC) 2029-02-02
NCT03347240 Neuroablation Versus Neuromodulation Techniques for Treatment of Secondary Dystonia https://ClinicalTrials.gov/show/NCT03347240 Completed Ain Shams University 2016-12-31
NCT01169324 Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders https://ClinicalTrials.gov/show/NCT01169324 Completed University of Alabama at Birmingham 2015-12-11
NCT00773604 Deep Brain Stimulation in Patients With Dystonia https://ClinicalTrials.gov/show/NCT00773604 Completed University of California, San Francisco 2015-02-28
NCT00773253 Botox for Cervical Dystonia Following EMG Mapping https://ClinicalTrials.gov/show/NCT00773253 Completed University of California, San Francisco 2010-10-31
NCT00703287 Specialized Physiotherapy Program for Cervical Dystonia https://ClinicalTrials.gov/show/NCT00703287 Completed South Glasgow University Hospitals NHS Trust 2010-05-31
NCT00702754 An Open Label Safety and Immunogenicity Study of MYOBLOC (Neurobloc; Botulinum Toxin Type B) Injectable Solution in Patients With Cervical Dystonia https://ClinicalTrials.gov/show/NCT00702754 Completed US WorldMeds LLC 2008-05-31
NCT00564681 Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia https://ClinicalTrials.gov/show/NCT00564681 Completed Allergan 2008-12-31
NCT00549341 PurTox (Botulinum Toxin Type A) for the Treatment of Adult Onset Spasmodic Torticollis/Cervical Dystonia https://ClinicalTrials.gov/show/NCT00549341 Completed Mentor Worldwide, LLC 2008-09-30
NCT00541905 Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia https://ClinicalTrials.gov/show/NCT00541905 Completed Merz Pharmaceuticals GmbH 2008-10-31
NCT00505323 Motor and Premotor Cortex Stimulation for Treatment of Secondary Focal Dystonia With Striato Palliadal Lesion : Evaluation of Safety and Effectiveness https://ClinicalTrials.gov/show/NCT00505323 Completed University Hospital, Clermont-Ferrand 2011-06-30
NCT00447772 Study to Assess the Efficacy and Safety of Dysport® in Cervical Dystonia https://ClinicalTrials.gov/show/NCT00447772 Completed Ipsen 2008-02-29
NCT00411255 Brain Stimulation to Treat Blepharospasm or Meige Syndrome https://ClinicalTrials.gov/show/NCT00411255 Completed National Institutes of Health Clinical Center (CC) 2009-04-07
NCT00407030 IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Cervical Dystonia https://ClinicalTrials.gov/show/NCT00407030 Completed Merz Pharmaceuticals GmbH 2008-01-31
NCT00331825 Risperidone and Olanzapine for the Schizophrenic Patients With Neuroleptic-Induced Acute Dystonia or Parkinsonism https://ClinicalTrials.gov/show/NCT00331825 Completed Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan NA
NCT00288509 Open-label Extension Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia https://ClinicalTrials.gov/show/NCT00288509 Completed Ipsen 2008-01-31
NCT00257660 Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia https://ClinicalTrials.gov/show/NCT00257660 Completed Ipsen 2006-09-30
NCT00208091 Quantifying Musical Performance After Treatment With Myobloc in Musician’s Dystonia https://ClinicalTrials.gov/show/NCT00208091 Completed Columbia University 2008-05-31
NCT00178945 Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain https://ClinicalTrials.gov/show/NCT00178945 Completed Vanderbilt University NA
NCT00169338 Pallidal Stimulation in Patients With Post-anoxic and Idiopathic Dystonia https://ClinicalTrials.gov/show/NCT00169338 Completed Groupe Hospitalier Pitie-Salpetriere 2014-01-31
NCT00165776 Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis https://ClinicalTrials.gov/show/NCT00165776 Completed Eisai Inc. 2006-05-31
NCT00148889 Double-blind, Multicenter Study to Assess the Efficacy of Bilateral Pallidal Stimulation in Patients With Medically Refractory Primary Cervical Dystonia https://ClinicalTrials.gov/show/NCT00148889 Completed German Parkinson Study Group (GPS) 2008-04-30
NCT00132990 A Multicenter Pilot Study of Pallidal Deep Brain Stimulation for Cervical Dystonia https://ClinicalTrials.gov/show/NCT00132990 Completed University of Calgary NA
NCT00132340 Deep Brain Stimulation to Treat Cervical Dystonia https://ClinicalTrials.gov/show/NCT00132340 Completed National Institutes of Health Clinical Center (CC) NA
NCT00122044 Childhood Hypertonia of Central Origin: A Trial of Anticholinergic Treatment Effects https://ClinicalTrials.gov/show/NCT00122044 Completed University of Southern California 2004-12-31
NCT00106782 Transcranial Electrical Polarization to Treat Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT00106782 Completed National Institutes of Health Clinical Center (CC) 2010-05-14
NCT00105430 Deep Brain Stimulation for Cervical Dystonia https://ClinicalTrials.gov/show/NCT00105430 Completed National Institutes of Health Clinical Center (CC) NA
NCT00021853 Motor Training to Treat Hand Dystonia https://ClinicalTrials.gov/show/NCT00021853 Completed National Institutes of Health Clinical Center (CC) NA
NCT00015457 Amlodipine Plus Botulinum Toxin for Focal Dystonia https://ClinicalTrials.gov/show/NCT00015457 Completed National Institutes of Health Clinical Center (CC) 2009-04-30
NCT00001784 Mexiletine for the Treatment of Focal Dystonia https://ClinicalTrials.gov/show/NCT00001784 Completed National Institutes of Health Clinical Center (CC) NA
NCT00004421 Deep Brain Stimulation in Treating Patients With Dystonia https://ClinicalTrials.gov/show/NCT00004421 Completed FDA Office of Orphan Products Development NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03380676 Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular https://ClinicalTrials.gov/show/NCT03380676 Completed University Hospital, Lille 2014-05-31
NCT03363113 Outcome of Botulinum Toxin Treatment for Oromandibular Dystonia https://ClinicalTrials.gov/show/NCT03363113 Completed Fondation Ophtalmologique Adolphe de Rothschild 2016-04-01
NCT03042962 Brain Networks in Dystonia https://ClinicalTrials.gov/show/NCT03042962 Active, not recruiting Massachusetts Eye and Ear Infirmary 2020-05-31
NCT03041714 Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor https://ClinicalTrials.gov/show/NCT03041714 Completed National Institutes of Health Clinical Center (CC) 2018-03-22
NCT03027310 Clinical and Physiological Studies of Tremor Syndromes https://ClinicalTrials.gov/show/NCT03027310 Recruiting National Institutes of Health Clinical Center (CC) 2022-01-01
NCT02894359 Computer Modelling of the Cervical Spine Movements in Cervical Dystonia https://ClinicalTrials.gov/show/NCT02894359 Completed Fondation Ophtalmologique Adolphe de Rothschild 2018-10-25
NCT02882295 Validation of the Zigzag Tracking Task Test for the Evaluation of Handwriting Difficulties in Writer’s Cramp https://ClinicalTrials.gov/show/NCT02882295 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2021-08-31
NCT02780336 Blepharospasm Tools https://ClinicalTrials.gov/show/NCT02780336 Completed Emory University 2019-03-20
NCT02689466 Cholinergic Receptor Imaging in Dystonia https://ClinicalTrials.gov/show/NCT02689466 Recruiting National Institutes of Health Clinical Center (CC) 2021-07-01
NCT02468843 Novel Stimulation Patterns for the Treatment of Dystonia https://ClinicalTrials.gov/show/NCT02468843 Completed University of Florida 2016-01-31
NCT02320266 Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery https://ClinicalTrials.gov/show/NCT02320266 Recruiting University of Colorado, Denver 2020-12-31
NCT02245958 A Retrospective Chart Review of BOTOX® and Xeomin® for the Management of Cervical Dystonia and Blepharospasm https://ClinicalTrials.gov/show/NCT02245958 Completed Allergan 2015-12-31
NCT02175719 Post-marketing Surveillance of Administration of Botulinum Toxin Type B(NerBloc)-Investigation of the Clinical Condition in Patients With Change From Botulinum Toxin Type A https://ClinicalTrials.gov/show/NCT02175719 Completed Eisai Inc. 2017-12-31
NCT02175693 Post-marketing Surveillance of Administration of Botulinum Toxin Type B(NerBloc)-Investigation of the Clinical Condition and Safety in Patients With Cervical Dystonia https://ClinicalTrials.gov/show/NCT02175693 Completed Eisai Inc. 2019-06-30
NCT02076581 MyoSense- Automated Muscle Hypertonicity Classification System https://ClinicalTrials.gov/show/NCT02076581 Completed Great Lakes NeuroTechnologies Inc. 2015-04-30
NCT02071446 Local Fields Potentials Recorded From Deep Brain Stimulating Electrodes https://ClinicalTrials.gov/show/NCT02071446 Completed University of Colorado, Denver 2017-11-29
NCT02069548 Analysis of Three-dimensional Movements of the Head in Cervical Dystonia https://ClinicalTrials.gov/show/NCT02069548 Completed Fondation Ophtalmologique Adolphe de Rothschild 2015-04-30
NCT01314365 DYSPORTâ„¢ Clinical & Health Economics Outcomes Registry in Cervical Dystonia https://ClinicalTrials.gov/show/NCT01314365 Completed Ipsen 2013-11-30
NCT01287247 Trial Evaluating Xeomin® (incobotulinumtoxinA) for Cervical Dystonia or Blepharospasm in the United States https://ClinicalTrials.gov/show/NCT01287247 Completed Merz North America, Inc. 2013-04-30
NCT02046447 Neuroimaging of Dystonia https://ClinicalTrials.gov/show/NCT02046447 Completed University of Florida 2015-12-31
NCT01888926 The Effects of Repetitive Paired Associative Stimulation in Dystonia https://ClinicalTrials.gov/show/NCT01888926 Completed National Institutes of Health Clinical Center (CC) 2016-08-02
NCT01840462 Longitudinal Study for Treatment With Botulinum Toxin A Injections in naïve and Pre-treated Patients Suffering From Cervical Dystonia [CD-NIS-Longterm] https://ClinicalTrials.gov/show/NCT01840462 Completed Ipsen 2015-11-30
NCT01809613 Functional Magnetic Resonance Imaging (fMRI) During Deep Brain Stimulation (DBS) to Treat Parkinson’s Disease https://ClinicalTrials.gov/show/NCT01809613 Completed Mayo Clinic 2017-07-27
NCT01761903 Functional Connectivity in Primary Focal Dystonia https://ClinicalTrials.gov/show/NCT01761903 Completed University of Colorado, Denver 2018-06-30
NCT01753349 Phase IV-Cervical Dystonia-INTEREST IN CD2 https://ClinicalTrials.gov/show/NCT01753349 Completed Ipsen 2017-09-30
NCT01705301 Neurotransmitter Measurements Using (WINCS) During Deep Brain Stimulation Neurosurgery https://ClinicalTrials.gov/show/NCT01705301 Completed Mayo Clinic 2017-07-27
NCT01671527 Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia https://ClinicalTrials.gov/show/NCT01671527 Completed University of Florida 2016-03-31
NCT01655862 A Prospective, Observational Study of Patients With Cervical Dystonia (Dystonie) Treated With OnabotulinumtoxinA https://ClinicalTrials.gov/show/NCT01655862 Completed Allergan 2017-02-28
NCT01579266 Validating a New Writer s Cramp Scale https://ClinicalTrials.gov/show/NCT01579266 Completed National Institutes of Health Clinical Center (CC) NA
NCT00713414 Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia https://ClinicalTrials.gov/show/NCT00713414 Completed National Institutes of Health Clinical Center (CC) NA
NCT01435681 Can Short Latency Afferent Inhibition Give us Clues to Better DYT 1 Dystonia Treatments? https://ClinicalTrials.gov/show/NCT01435681 Completed University of Florida 2014-10-31
NCT01432899 Studying Childhood-Onset Hemidystonia https://ClinicalTrials.gov/show/NCT01432899 Completed National Institutes of Health Clinical Center (CC) NA
NCT01373840 Role of Dopamine Receptors in Primary Focal Dystonias https://ClinicalTrials.gov/show/NCT01373840 Completed Washington University School of Medicine 2016-04-30
NCT01373424 The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias https://ClinicalTrials.gov/show/NCT01373424 Recruiting Emory University 2020-07-31
NCT04432285 Long-term Outcome of DBS Versus Botulinum Toxin Treatment in Cervical Dystonia https://ClinicalTrials.gov/show/NCT04432285 Enrolling by invitation Oslo University Hospital 2021-12-31
NCT04231487 Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders https://ClinicalTrials.gov/show/NCT04231487 Recruiting Rutgers, The State University of New Jersey 2021-12-31
NCT03992625 Clinical Outcomes for Deep Brain Stimulation https://ClinicalTrials.gov/show/NCT03992625 Recruiting Washington University School of Medicine 2030-01-01
NCT03969537 Telemedicine Follow-up for Patients With Cervical Dystonia Treated With Neurotoxin Injections https://ClinicalTrials.gov/show/NCT03969537 Enrolling by invitation Vanderbilt University Medical Center 2020-10-01
NCT03884231 MRI Study of Infinity DBS System https://ClinicalTrials.gov/show/NCT03884231 Recruiting Abbott Medical Devices 2021-04-30
NCT03857607 Natural History Study of ATP1A3-related Disease https://ClinicalTrials.gov/show/NCT03857607 Active, not recruiting Institute of Child Health 2020-08-31
NCT03717376 Movement Disorders and Early Maladaptive Schemas https://ClinicalTrials.gov/show/NCT03717376 Recruiting Assistance Publique - Hôpitaux de Paris 2020-02-12
NCT03664609 Deep Brain Stimulation (DBS) Retrospective Outcomes Study https://ClinicalTrials.gov/show/NCT03664609 Recruiting Boston Scientific Corporation 2028-06-29
NCT03471923 Non-Motor Features of Cervical Dystonia (CD) https://ClinicalTrials.gov/show/NCT03471923 Completed Vanderbilt University Medical Center 2019-12-02
NCT03428009 Dystonia Genotype-Phenotype Correlation https://ClinicalTrials.gov/show/NCT03428009 Recruiting University of Texas Southwestern Medical Center 2021-02-21
NCT01210534 Physiological Brain Atlas Development https://ClinicalTrials.gov/show/NCT01210534 Active, not recruiting Ohio State University 2020-08-31
NCT01180270 Static Graviceptive Functions in Patients With Cervical Dystonia (CD) https://ClinicalTrials.gov/show/NCT01180270 Completed Medical University of Vienna 2012-01-31
NCT01168388 Movement Disorder Survey in East China https://ClinicalTrials.gov/show/NCT01168388 Completed Sir Run Run Shaw Hospital 2010-08-31
NCT01056861 Effects of Botulinum Toxin in Cervical Dystonia https://ClinicalTrials.gov/show/NCT01056861 Completed Henry Ford Health System 2014-07-31
NCT00954408 Fatigue in Dystonia (a Single Session, Questionnaire-based Study of Fatigue in Dystonia) https://ClinicalTrials.gov/show/NCT00954408 Completed University of Florida 2011-07-31
NCT00836017 CD-PROBE: Cervical Dystonia Patient Registry for the Observation of onabotulinumtoxinA Efficacy https://ClinicalTrials.gov/show/NCT00836017 Completed Allergan 2013-08-31
NCT00833196 Factors Influencing Response to One BoNT-A Injection Cycle in Subjects Suffering From Idiopathic Cervical Dystonia https://ClinicalTrials.gov/show/NCT00833196 Completed Ipsen 2010-02-28
NCT01814774 A Retrospective Chart Review of BOTOX® and Xeomin® for the Treatment of Cervical Dystonia and Blepharospasm https://ClinicalTrials.gov/show/NCT01814774 Completed Allergan 2013-07-31
NCT04071847 Abbott DBS Registry of Outcomes for Indications Over Time https://ClinicalTrials.gov/show/NCT04071847 Recruiting Abbott Medical Devices 2029-09-30
NCT00792532 Use of Interventional MRI for Implantation of Deep Brain Stimulator Electrodes https://ClinicalTrials.gov/show/NCT00792532 Completed University of California, San Francisco 2019-03-31
NCT00682513 Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders https://ClinicalTrials.gov/show/NCT00682513 Active, not recruiting University of California, Davis 2021-03-31
NCT00595439 Association Between Focal Dystonia and Complex Regional Pain Syndrome https://ClinicalTrials.gov/show/NCT00595439 Completed National Institutes of Health Clinical Center (CC) 2009-10-05
NCT00575081 Physiological Brain Atlas Development https://ClinicalTrials.gov/show/NCT00575081 Recruiting Vanderbilt University Medical Center 2023-07-31
NCT00472914 Use of EMG to Assess Clinical Hypertonia https://ClinicalTrials.gov/show/NCT00472914 Completed University of Southern California NA
NCT00465790 Research of Biomarkers in Parkinson Disease https://ClinicalTrials.gov/show/NCT00465790 Completed Institut National de la Santé Et de la Recherche Médicale, France 2012-06-30
NCT00376753 Muscle Contraction in Patients With Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT00376753 Completed National Institutes of Health Clinical Center (CC) NA
NCT00361465 DYSCAR: Characterization of Dystonia https://ClinicalTrials.gov/show/NCT00361465 Completed University Hospital, Grenoble NA
NCT00325091 Long-Term Motor Learning in Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT00325091 Completed National Institutes of Health Clinical Center (CC) NA
NCT00323765 Plasticity in Cervical Dystonia https://ClinicalTrials.gov/show/NCT00323765 Completed National Institutes of Health Clinical Center (CC) NA
NCT00310414 fMRI Studies of Task Specificity in Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT00310414 Completed National Institutes of Health Clinical Center (CC) NA
NCT00309010 Neurophysiology of Task-Specificity of Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT00309010 Completed National Institutes of Health Clinical Center (CC) NA
NCT00306865 Brain Changes in Patients With Focal Hand Dystonia https://ClinicalTrials.gov/show/NCT00306865 Completed National Institutes of Health Clinical Center (CC) NA
NCT00285870 Quantification of Upper Extremity Hypertonia https://ClinicalTrials.gov/show/NCT00285870 Completed University of Southern California 2012-12-31
NCT00210431 Post Marketing Surveillance Study of Dysport https://ClinicalTrials.gov/show/NCT00210431 Completed Ipsen NA
NCT00137384 Movement-Related Brain Networks Involved in Hand Dystonia https://ClinicalTrials.gov/show/NCT00137384 Completed National Institutes of Health Clinical Center (CC) NA
NCT00118586 Neuropathology of Spasmodic Dysphonia https://ClinicalTrials.gov/show/NCT00118586 Active, not recruiting National Institutes of Health Clinical Center (CC) NA
NCT00102999 Brain Function in Focal Dystonia https://ClinicalTrials.gov/show/NCT00102999 Completed National Institutes of Health Clinical Center (CC) NA
NCT00082615 Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives https://ClinicalTrials.gov/show/NCT00082615 Completed National Institutes of Health Clinical Center (CC) NA
NCT00072956 The Physiology of Tricks https://ClinicalTrials.gov/show/NCT00072956 Completed National Institutes of Health Clinical Center (CC) NA
NCT00054652 Survey of Sensory and Motor Tricks in Focal Dystonia https://ClinicalTrials.gov/show/NCT00054652 Completed National Institutes of Health Clinical Center (CC) NA
NCT00050024 Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal Dystonia https://ClinicalTrials.gov/show/NCT00050024 Completed National Institutes of Health Clinical Center (CC) NA
NCT00047957 Brain Inhibition of Muscle Movement in Normal Volunteers https://ClinicalTrials.gov/show/NCT00047957 Completed National Institutes of Health Clinical Center (CC) NA
NCT00029601 Surround Inhibition in Patients With Dystonia https://ClinicalTrials.gov/show/NCT00029601 Completed National Institutes of Health Clinical Center (CC) NA
NCT00025701 EEG and EMG Studies of Hand Dystonia https://ClinicalTrials.gov/show/NCT00025701 Completed National Institutes of Health Clinical Center (CC) NA
NCT00006336 Sensory Training to Treat Focal Dystonia https://ClinicalTrials.gov/show/NCT00006336 Completed National Institutes of Health Clinical Center (CC) NA
NCT00017875 Transcranial Magnetic Stimulation (TMS) Studies of Dystonia https://ClinicalTrials.gov/show/NCT00017875 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02959645 Assessment of Brain Activities in Cervical Dystonia https://ClinicalTrials.gov/show/NCT02959645 Recruiting University of Minnesota 2020-07-31
NCT02686125 Registry of Deep Brain Stimulation With the VERCISEâ„¢ System for Treatment of Dystonia: Vercise DBS Dystonia Registry https://ClinicalTrials.gov/show/NCT02686125 Recruiting Boston Scientific Corporation 2027-12-31
NCT04023656 Prognosis of Paroxysmal Kinesigenic Choreoathetosis in Korea https://ClinicalTrials.gov/show/NCT04023656 Recruiting Seoul National University Hospital 2026-12-31
NCT03892798 Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene https://ClinicalTrials.gov/show/NCT03892798 Recruiting Children’s Hospital Medical Center, Cincinnati 2038-12-31